Cause of fibrous papules facial angiofibroma

NCBI Bookshelf. Cutaneous angiofibroma is a term used to define a group of lesions with different clinical presentations but with the same histologic findings. Both facial angiofibromas greater than or equal to 3 needed and periungual angiofibroma greater than or equal to 2 needed are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 MEN-1 and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
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01.04.2021
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Fibrous papule of the nose and face

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ACD A-Z of Skin - Angiofibroma

DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages. Copy edited by Gus Mitchell. April A cutaneous angiofibroma is a benign vascular neoplasm composed of dermal fibrous tissue and blood vessels. Angiofibroma is classified by association with a genetic disorder or according to its body site [1]. Tuberous sclerosis is a neurocutaneous autosomal dominant syndrome, in which angiofibromas appear in childhood in the nasolabial folds and on the central face [2].
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Dermatology Online Journal

Home » Decision Support in Medicine » Dermatology. Fibrous papule aka solitary angiofibroma is a common benign skin growth. As a solitary lesion, there are no associated systemic implications. When multiple angiofibromas are seen in an individual, particularly clustered over the central face, the differential diagnosis should include the tuberous sclerosis complex, and appropriate evaluation should ensue to assess the patient for tuberous sclerosis. Multiple facial angiofibromas may also be seen as the presenting sign or in association with multiple endocrine neoplasia type 1.
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Numerous angiofibromas on the face are commonly associated with tuberous sclerosis or multiple endocrine neoplasia type 1. A year-old healthy woman was referred to our practice for evaluation of multiple skin-colored papules on the face. Biopsies were taken from four of the lesions for histopathologic examination.
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